Saturday, 3 March 2012

EMERGING TRENDS IN BIOTECHNOLOGY, SEMESTER III, MSc. BIOTECHNOLOGY CURRICULUM- 2009-2011


304 EMERGING TRENDS IN BIOTECHNOLOGY

Unit I

1. Genome & Genomics: Concept and methods of genome analysis, genome projects.
2. Transcriptome & Transcriptomics: Concept and methods
3. Proteome & Proteomics: Concept and methods of Proteome analysis
4. Metabolome & Metabolomics

Unit II

1. Stem Cell technology: Types of stem cells
2. Manipulations of stem cells and applications in medicine
3. In vitro fertilization: Principle, methods, applications and ethics.
4. Cloning of animals: Methods and applications.

Unit III

1. Nano biotechnology: Introduction, Biomaterials and biological materials-examples and
uses
2. DNA nanotechnology-structural DNA assembly-Nanopore and
3. Nanoparticles-biological arrays- nanoprobes for analytical applications
4. Nano biosensors-nanoscale organization-characterization-quantum size effects- sensors
of the future.
5. Tools for measuring nanostructures. Microscopies-SEM-TEM-AFM modern advancesmicroanalysis-
optical detection of single molecules

Unit IV

1. Microarray chips: Concept, design of biochip, types of DNA chips
2. Gene Therapy for Human Diseases.
3. Protein Crystallization; Theory and methods: API Electro spray and MALDI-TOF.
4. SNP’s and GMS (Genome mismatch Signals)

Unit V

1. Biosensors: Concept, principle, Organization of biosensors
& types
2. Biosensors: Health & Medicine
3. Biosensors: Food technology, Environment monitoring
4. Bacterial biosensors; Array Biosensors

Practical Exercises: Appropriate exercises based on theory

Reference Books

1. DNA Microarrays and gene expression by P. Baldi & GW Hatfield
2. Protein – Protein Interactions by Erica Golemis
3. A passion for DNA (Genesm genomes and Society) By JD Watson
4. Modern Genetic analysis by Anthony JF Griffiths et al.
5. Nan biotechnology- next big idea by Mark, Ratner Daniel Ratner
6. Gene cloning by TA Brown
7. Latest information on academic Web sites.

Note: All books are of latest editions

305. Lab Course V
Consists of practical exercises listed out under 301 & 302

306. Lab Course VI
Consists of practical exercises listed out under 303 & 304

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