Revised Syllabus
To be introduced from
the academic year 2010-11
(i.e. from June 2010
) Onwards
(Subject to the
modifications will be made from time to time)
B E –(Chemical)
(To be introduced
from June, 2010 )
1.
CHEMICAL REACTION ENGINEERING-II
Examination
Lectures
: - 4 hrs per week Theory : 100
Practical
/Oral
Practical
: 2 hrs/batch Internal : 25
External : 25
Non
Ideal Flow : (7)
Basic concept:
conversion in reactors having non ideal flow; The Residence Time
Distribution
Functions and their Relationships Determining RTD from Experimental
Tracer Curves Tubular
Reactor E- and F-Curves for a Series of Stirred Tank Reactors
Analysis of RTD from
Pulse Input and step input Models for predicting conversion from
RTD data: Zero
Parameter : Segregation and Maximum mixedness model ; One
Parameter :
Dispersion model, Tank in Series model, Introduction to Multi parameter
model.
Mixing
of fluids: (4)
Self-mixing of single
fluid. Early and late mixing of fluid, models for partial segregation,
mixing of two
miscible fluids, Model Effect of Micromixing on Conversion Time-
Dependent Turbulent
Mixing and Chemical Reaction in Stirred Tanks. Improve
Performance of
Reactors Via Computational Fluid Dynamics
Heterogeneous
processes and Solid catalysts : (7)
Global rate of
reaction, Catalysis, Nature of catalytic reactions, adsorption isotherm,
Rates of adsorption.
Determination of Surface area, Void volume and solid density, Pore
volume distribution,
Classification of catalysts, Catalyst preparation, Promoters and
inhibitors
Fluid
particle reactions ( Non catalytic ) : (5)
Selection of a model
for gas-solid reactions Un-reacted core and Shrinking core model,
Rate controlling
resistances, Determination of the rate controlling steps, Application of
models to design
problems
Fluid
- fluid reaction (6)
Introduction to
heterogeneous fluid - fluid reactions, Rate equation for instantaneous ,
Fast and slow
reaction, Equipment used in fluid- fluid contacting with reaction,
Application of fluid
-fluid reaction rate equation to equipment design, Towers for fast and
slow reactions.
Solid
catalyzed reactions : (6)
Introduction, Rate
equation, Film resistance controlling, surface flow controlling , Pure
diffusion controlling,
Heat effects during reaction, Experimental methods for finding
rates, ,
construction, operation and design of Catalytic reactors : Fixed bed reactor,
Fluidized bed
reactor, Multiphase reactors : Slurry reactor, Trickle bed reactor.
Isothermal and non
isothermal reactor design ( batch reactor only)
Deactivating
catalysts(4)
Types of Deactivation
, Mechanism of deactivation, Rate equation for deactivation,
Regeneration of
catalyst
Scale-Up
in Reactor Design: (6)
Factors affecting
choice of reactor. Reactor stability Development and Scale-Up of
Reactors Similarity
Criteria , Scale-Up in Relation to Various Factors Heat Effect ,
Coefficients of
Process Stability Dimensional Analysis and Scale-Up Equations
Mathematical Modeling
Scale-Up of a Batch Reactor
Heat Transfer Model
Jacket Zoning of a Batch Reactor The Outlet Temperature of a
Scaled-Up Batch
System Aspect Ratio (R) in Jacket Zoning and Scale-Up of a Batch
Reactor
Practical
:
1. Studies on
homogeneous batch reactor.
2. RTD Studies on
tubular flow reactor.
3. RTD Studies on
mixed flow reactor.
4. RTD Studies on
mixed flow reactor in series.
5. Residence time
distribution studies in structures and coils.
6. RTD Studies on
packed bed reactor.
7. Determination
Surface area of catalysts
8. Determination Pore
volume of catalysts
9. Determination of
bulk density, apparent density, and true density of catalyst.
10. Studies on
general liquid reactions
Text
Books
1. Octave Levenspiel,
“Chemical Reaction Engineering”, 3 rd Edition, John Wiley,
London.
2. S.H. Fogler,”
Elements of Chemical Reaction Engineering”, PHI, 4 th Edition.
3. J.M. Smith,
“Chemical Engineering Kinetics”, 3rd Edition, McGraw Hill, New
York 1981.
References:
1 T.T. Carbery,
“Chemical and Catalytic reaction Engineering”, McGrawHill, New
York - 2001.
2. Modeling
of Chemical Kinetics and Reactor Design
A. Kayode Coker, Gulf
Publishing House New Delhi
3. Chemical
Reactor Design
Peter Harriot Marcel
Dekker, Inc. New York
4. Chemical
Engineering Vol. III
Pergamon Press,
Oxford, 1989.
5. Introduction to
Chemical Reaction Engineering and Kinetics
Ronald W. Missen
Charles A. Mims Bradley A. Saville
John
Wiley & Sons, Inc.
6. Chemical Reactor
Design Optimization and Scaleup
E. Bruce Nauman
McGrawHill, New York - 2001.
2.
CHEMICAL PROCESSES AND SYNTHESIS
Examination
Lectures:
- 3 hrs per week Theory : 100
Practical
/Oral -- Practical:
Internal
: --
External
: --
1.
Chemical Processing and work of chemical engineer.
2.
Industrial Gases: Hydrogen, Oxygen, Nitrogen, Carbon Dioxide, Acetylene
3. Glass
and Refractories: Basic raw materials, Manufacturing of refractories, Glass
raw materials,
Manufacturing, Types and Applications.
4.
Fuels and Fuel gases: Natural gas, Water gas, Producer gas, LPG.
5.
Chloro – alkali and electrolytic industries: Soda ash, caustic
soda, Chlorine,
Bleaching powder,
Sodium bicarbonate, Aluminum, Sodium, Chlorates and perchlorates.
6.
Hydrochloric acid: Hydrochloric acid, Aluminum sulphate and alums.
7.
Phosphate industries: Elemental phosphorous, Raw materials and process for
phosphoric acid,
Manufacturing of ammonium phosphate, Baking powder.
8.
Potassium industries: Potassium, Potassium chloride, Potassium sulfate,
Potassium nitrate.
9.
Nitrogen industries: Synthetic ammonia, Nitric acid, Ammonium nitrate, Urea
10.
Sugar and Starches : Sugar and Starches
11.
Fermentation Industry : Absolute Alcohol, Beer , wines &
liquors , vinegar ,
citric acid and
lactic acid .
Text
Book:
1. George T. Austin,
“Shreve's Chemical Process Industries”, 5th edn. , McGraw
Hill Book Company, 1985.
References:
1. S.D. Shukla, G.N.
Pandey, “A Text book of Chemical Technology”, 3rd Edition
2. C.E. Dryden,
“Outlines of Chemical Technology”, Affiliated East-West Press,
1973.
3. D. Venkteshwaralu,
“Chemical Technology”, I & III manuals of Chemical
Technology Chemical
Engg. Ed. Dev. III Madras, 1977.
4. Faith, “Industrial
Chemicals”. Rogers, “Industrial Chemistry”.
3.CHEMICAL
PROCESS DESIGN (CPD)
(New
Revised) Examination
Lectures
: - 4 hrs per week Theory : 100 (4 hrs. Question Paper)
Practical
/Oral
Practical
: 2 hrs/batch Internal : 25 External :
25
1.
The nature and function of process design.
2.
Flow sheet preparation and drawing: Sketching techniques,
Equipment lettering and
numbering, Equipment
symbols, Instruments symbols, Stream designations for process
and utility,
3.Process
Planning Scheduling and Flow Sheet Design –Organizational structure,
Process design scope,
Types of flow sheets, P and I diagrams, Types of P and IDs, Issues
in P and IDs, P and
IDs presentation.
4.
Piping Design: Pipe codes, Layout, Pipe Support design, Thermowell design --
Types,
Material of
construction, Installing methods and pipe thread sizes, Piping installation,
Pump size selection.
5.
Design Information and Data: General sources of physical
properties, Predication of
physical properties,
Accuracy required in engineering data, Specification and design of
process equipment,
Rules of THUMB for design of equipment, Software use in process
design.
6.
Process Heat Transfer , Conduction, Convection, Radiation,
Temperature.
7.
Counter Flow: Double pipe heat exchanger.
8. 1-
2 Parallel counter flow: Shell and Tube heat exchangers.
9.
Flow arrangements for increased heat recovery.
10.
Calculation for process conditions.
11.
Condensation of single vapours.
12.
Evaporation (M.E.E.)
13.
Design of Agitated Batch Reactor.
14.
Design of Binary Distillation Column with packed and sieve trays.
15.
Design of Rotary Dryer.
16.
Design of Gas-Solid Cyclone Separator.
Note: The necessary
data / tables / charts / graphs are to be supplied during the theory
examination by the
respective institutes.
Books/References:
1. A.
K. Koker, “Fundamentals of Equipment Design”, Gulf Publication.
2.
D.Q. Kem, “Process Heat Transfer”, Tata McGraw Hill Company, New York, 1997.
3.
E.E. Ludwig, “Applied Process Design for Chemical and Petrochemical Plants”,
Vol.I,II,III, Gulf
Publication, 3rd edition London, 1994.
4.
G.D.Ulrich, “A Guide to Chemical Engineering Process Design and Engineering”,
John Wiley and Sons,
New York, 1984.
5. .
M.S. Peters & K.D.Timmerhaus, “Plant Design and Economics for Chemical
Engineers”, 5th edition,
McGraw Hill International Book Co.,2003.
6. J.
J. McKetta, “Piping Design Handbook”, Marcel Dekker inc., New York, 1992.
7. J.
M. Smith,“Chemical Engineering Kinetics”,3rd edition
McGraw Hill, New York1981
8.
J.M. Coulson, “Chemical Engg.”, Vol. VI, Pergamon Press, Oxford, 1989.
9.
McCabe W.L. and Smith J.C. ‘Unit operations of Chemical Engg.’ 7th ed.McGraw
Hill Book Co.,
International ed. 2005.
10.
Octave Levenspeil, “Chemical Reaction Engineering”, 2nd Edition, John Wiley,
11. R.
E. Treybal, “Mass Transfer Operations”, 3rd Edition, McGraw Hill Company,
Singapore, 1980.
12.
R.H. Perry & Don W. Gress, “Perry's Chemical Engg.”, Hand-book , 7th Edition
McGraw Hill Company,
New York, 1997.
13. S.
M. Walas, “Reaction Kinetics for Chemical Engineers” McGraw Hill, New York.
14.
S.D. Dawande, “Process Design of Equipment”, Dennet Publication, Vol. I and II,
5th
Edition 2005.
15.
S.H. Fogler, “Elements of Chemical Reaction Engineering”, Prentice Hall
Publication, 3rd
edition.
16.
Vilbrant F. L. and Dryden C.E., “Chemical Engineering Plant Design”, McGraw
Hill
Company, New York
1959.
FOR
TERM WORK ONLY
Detailed
drawing of the following
1. Equipment
symbols
2. Instrument
symbols and stream designations
3. P
and I diagrams
Any
one type of the following
4. Exchanger
5. Condenser
6.
Evaporator
7. Agitated
Reactor
8.
Distillation Column
9.
Rotary Dryer.
10.
Gas - Solid Cyclone Separator
Note:
Maximum 10 sheets needed to be drawn, out of which 4 should be
drawn with the
help of software
AutoCAD.
4.
MODELING AND SIMULATION IN CHEMICAL ENGINEERING
Examination
Lectures:
- 4 hrs per week Theory: 100
Practical
/Oral
Practical:
- 2 hrs per week/batch Internal: 25
External:
25
L=Lecture
Section
I
1. Basic
Modeling: Introduction to modeling – Types of Models, Dependent &
Independent
Variables, Application and scope coverage, Modeling fundamentals,
Chemical engineering
modeling, several aspects of the modeling approach, general
modeling procedure.(5L)
2.
Formulation of dynamic models: Mass balance equation -
Balancing procedure, Case
studies: CSTR,
Tubular reactor, Coffee percolator, Total mass balance – Case Studies:
Tank drainage,
Component balances - Case Studies: Waste holding tank, Energy balance-
Heating in a filling
tank, Parallel reaction in a semi continuous reactor with large
temperature
difference, Momentum balances – Dimensionless model equations, CSTR,
Gas liquid mass
transfer in a continuous reactor.(7L)
3.
Modeling of stage wise processes: Introduction, Stirred tank
reactor, Reactor
Configurations,
Generalized model description, Heat transfer to and from
reactors, Steam
heating in jacket, Dynamics of the metal jacket walls, Batch
reactor – Constant
volume, Semi - batch reactor, CSTR - Constant volume CSTR, CSTR
cascade, bubble
column reactor, Reactor stability.(10L)
Section
II
4.
Mass transfer models: such as liquid-liquid extraction,
distillation, multicomponent
separation,
multicomponent steam distillation, absorber- stage wise absorption, steady
state gas absorption
with heat effects, evaporator.(5L)
5.
Dynamic modeling: Plug flow reactor, Plug flow reactor contactors, Liquid –
liquid extraction
column dynamics.(6L)
6.
Lumped and distributed system: Distributed system- Counter
current heat
exchanger, Flasher
design, Condensation, Definition of lumped parameter model.(4L)
7.
Simulation of chemical engineering: Process simulation, Scope of
process
simulation,
Formulation of problem, Step for steady state simulation, Process
simulation approaches
for steady state simulation, Strategies, Process simulator,
Structure of process
simulator, Integral process simulation, Simulation tools,
ISIM, Case studies:
Studies of integrated process simulation, ICAS – Integrated
Computer Aided
System, Sequential modular method. (5L)
List
of Practicals:
1. Mathematical
modeling and simulation of gravity flow tank.
2. Mathematical
modeling and simulation of CSTR.
3. Mathematical
modeling and simulation of multicomponent distillation column.
4. Mathematical
modeling and simulation of liquid – liquid extraction column.
5. Mathematical
modeling and simulation of heat exchanger.
6. Mathematical
modeling and simulation of lumped parameter model of column
Tray.
7. Mathematical
modeling and simulation of complex batch reactor.
Books:
1. C. L. Smith, R. L.
Pike and P. W. Murill, “Formulation Optimization of
Mathematical Models”,
International Text, Pennsylvania, 1970.
2. W. L. Luyben,
“Process Modeling, Simulation and Control for Chemical
Engineering”, McGraw
Hill Book co., 1973.
3. John Ingham,
Irving, J. Dunn, Elmar, Heinzle Jiri, E. Prenosil, “Chemical
Engineering
Dynamics”, VCH Publishers Inc., New York, 1974.
4. Roger G. E.
Franks, “Modeling and Simulation in Chemical Engineer”, Wiley
Inter Science, New
York, 1972.
5. R. W. Gaikwad, Dr.
Dhirendra, “Process Modeling and Simulation”, Central
Techno Publications,
Nagpur, 2003.
5.
ELECTIVE – I
1.PETROLEUM
REFINERY ENGINEERING
Lectures:
- 3 hrs per week Examination
Theory: 100
Practical
/Oral
Practical:
-- Internal : --
External:
--
Section
I
1.
Introduction to petroleum refineries: (3 Hrs.)
Resources of
petroleum, petroleum industries in India and world.
2.
Origin and exploration techniques: (3 Hrs.)
Origin of petroleum,
methods of exploration, drilling rigs, drilling techniques, production
methods of crude oil,
etc.
3
.Pre-refining operations: (3 Hrs.)
Composition of crude,
classification of crude, types of distillation methods, pretreatment
of crude, atmospheric
distillation, vacuum distillation, transportation of crude.
4. Properties and
specifications of petroleum products: (4 Hrs.)
properties and
specifications of fuel gas, LPG, gasoline, naphtha, jet fuel, kerosene,
diesel, lubricating
oils, greases, waxes, coke, etc.
5. Separation
processes: Solvent extraction processes, solvent de-waxing. (3 Hrs.)
Section
II
6. Conversion
process: (5 Hrs.)
Thermal cracking,
visbreaking, coking, catalytic cracking, thermal reforming, catalytic
reforming,
hydrocracking, hydroprocessing, alkylation, isomerisation and
polymerization.
7.
Treatment methods: (3 Hrs.)
Sweetening process,
hydrodesulphurization, smoke point improvement.
8.
Post production operations: (3 Hrs)
Blending of
additives, storage of products, transportation of products, housekeeping,
marketing of
petroleum and petroleum products, safety and pollution considerations in
refineries.
9.
Recent trends in petroleum refineries: (3 Hrs)
Recent trends in
petroleum in terms of Distillation, Packing materials, Catalyst, etc.
Note: A Case study on
the petroleum refineries may be taught.
Books:
1. Gary J H,
Handwerk G E, ‘Petroleum refining’
2. Nelson W. L.,
“Handbook of Petroleum Refinery Engg.”, McGraw Hill, International,
Auckland,1982.
3. Hobson G.D., Phol
W., “Modern Petroleum Technology-I”, 5th ed., Halsted Press,
Division of Wiley
Eastern New York, 1984.
4. Guthre, V.B.,
“Petroleum Products”, Hand-Book McGraw Hill.
5. Kobe, K.Q.
Mcketta, J.J. “Advances in Petroleum Chemistry and Refining”
Interscience.
6. J. M. Spight, “The
chemistry and technology of petroleum”
5.
ELECTIVE – I
2.
BIO-TECHNOLOGY
Examination
Lectures
: - 3 hrs per week Theory : 100
Practical
/Oral
Internal
: -
External
: -
________________________________________________________________________
1.
Introduction.
The pre – Pasteur
era, Pasteur era, The antibiotic era, New Biotechnology era, Impact of
New Biotechnology on
production of food, Chemicals and energy, Biotechnology as
interdisciplinary
science, Role of Chemical Engineering in Biotechnology. (3)
2.
Fundamentals of Biotechnology.
Cell structure and function,
Prokaryotes and Eukaryotes, arch bacteria, Extremophiles,
Structure and
function of microbial (Bacteria, yeast, fungi, algae, virus), Plant and animal
cells and cell
division mitosis, meiosis. (4)
3.
Biological macromolecules and Biochemistry.
Structure and
Function of – Carbohydrates, Proteins, Nucleic Acids and Lipids, steroids,
Importance of
sterospecificity of biomolecules, Chemistry of life, Chemical evaluation,
Intermediary
metabolism – anabolism/catabolism, Primary and secondary metabolism,
Central metabolic
pathways (Glycolysis, Citric acid cycle, gluconeogenesis),
interconversion of
metabolites, Regulation of metabolic pathways, Bioenergetics,
Photosynthesis. (7)
4.
Cellular Genetics and Genetic Engineering.
Nucleic Acid
metabolism (DNA, RNA synthesis) and protein synthesis, Menderian
genetics, Bacterial
genetics, (Transformation, Translation, Conjugation),
Induction/Repression,
Mutation. Genetic Engineering: Plasmid and cloning vehicles,
Plasmid stability
,Genetically modified bacteria in bioreactor , strain construction , Fplasmid
and genetic,
Recombination , Analysis of DNA molecule, Cloning consideration,
Cloning vector, host,
etc. DNA isolation, SI nuclease mapping, Applications of
recombinant DNA, DNA
hybridization, , Fingerprinting, Foot printing, Human genome
project, Ballistic
missiles, Gel electrophoresis (8)
5.
Enzymology and Enzyme Kinetics.
History, Structure
and function relation of enzymes, Classification, Properties of enzymes
as catalyst, General
features of enzymes, Enzyme sources, Enzyme purification and
characterization,
Basic enzyme kinetics, The action of effecter on enzyme activity.
Enzyme technology -
Immobilized enzyme technology, Non – aqueous enzyme
technology,
Immobilized enzymes, Immobilized cells, methods of cell Immobilizations,
Industrial
applications of enzyme. (5)
6.
Fermentation.
Microbial staining,
Growth of virus/phages, Microbial growth kinetics, Fundamental of
fermentation,
submerged fermentation, solid state fermentation (Ethanol, antibiotics,
enzyme dairy products),
Fermentation kinetics. (3)
7.
Media Preparation and Sterilization.
Synthetic and natural
media, Media preparations, Industrial medium, Nitrogen source,
Product formation,
sterilization and methods of sterilization (3)
8.
Practical Applications of Biotechnology in – Manufacturing and uses of
following.
a. Amino acids: L –
lysine, L – glutamate, L – phenylalanine.
b. Organic acids:
Citric acids, Lactic acids, etc.
c. Antibiotics:
Penicillin, Cephanlosporins, New beta – lacto technologies.
d. Bakers yeast
production.
e. Uses of enzymes in
sugar chemistry / mfg. of peptides.
f. Recombinant DNA
technology.
g. Tissue culture:
Animal and plant cell culture, monoclonal antibodies, transgenic plants
and animals.
h.Introduction to
bioremediation, Biosensors, Bio fuel cells, Biosurfactants, Biopolymers,
Bioenergy Park
i. Waste treatment.(4)
9.
The business of Biotechnology and its scope.
Informal sectors and
small entrepreneurs, some biotechnology industries/companies
in India. (2)
10.
Introduction to intellectual property protection in biotechnology. (1)
References:
1. A. H. Scragg,
“Biotechnology for Engineers”, Ellis Harwood Ltd.
2. Prescott, Harley
& Klein “Microbiology” 6th edition McGraw Hill
publication.
3. David Bourgaize et
al., “Biotechnology”, Pearson Education Inc., 2003.
4. H. D. Kumar, “Text
Book on Biotechnology”, Affiliated – East – West pvt. Ltd.,
New Delhi, 2nd
Edition, 2000.
5. V.K. Joshi &
Ashok Pandey “Biotechnology” food fermentation, vol 1, EPD
publication,
Ernakulam, Kerala.
6. Colin Ratledge et.
al., “Basic Biotechnology”, Cambridge University Press, 1st
edition, 2003.
7. Susan R. Barnum,
“Biotechnology”, Vikas Publishing House, 1st edition, 2001.
8. Wiseman, "
Principles of Bio-Technology."
9. Ayyanna, C.Ital,
“Bio-technology in the 21st century”, New Delhi,TMH-1993.
10. Trehan Keshav,
“Bio-technology”, Wiley Eastern Ltd, New Delhi,1991.
11. Lehninger A.L.
“Biochemistry”, Worth Publications Inc., New York,1972.
5.
ELECTIVE – I
3.
INTRODUCTION TO CRYOGENIC ENGINEERING
Lectures:
- 3 hrs per week Examination
Theory: 100
Practical
: -- Practical / Oral
Internal
: --
External:
--
Application areas of
cryogenics, Methods of producing cryogenic temperatures and
energy / exergy
considerations. Gas liquefaction processes, Commercial liquefiers and
cryogenic
refrigerators, cryogenic recovery and purification of industrial gases.
Thermophysical
properties at cryogenic temperatures. Process design considerations for
cryogenic
separations. Storage and transportation of cryogenic fluids. Cryogenic
insulations and
vacuum technology, Measurement techniques and instrumentation.
Materials of
construction and their behavior at cryogenic temperatures.
Books:
1. R. Barron,
“Cryogenic Systems”, 2nd ed., McGraw Hill, 1985.
2. G.G. Haselden,
“Cryogenic Fundamentals”, Academic Press, 1971.
5.
ELECTIVE – I
4.
PHARMACEUTICAL TECHNOLOGY – I
Examination
Lectures
: - 3 hrs per week Theory : 100
Practical
/Oral : -- Practical :
Internal
: -
External
: -
Discussion of
monographs such as limit test, LOD, ash value, saponifiction value,
ester acid value,
determination of volatile oils etc., Inorganic chemicals of
Pharmaceutical
importance with respect to their manufactures and uses, assay methods,
Chemotherapeutic
agents, Antiinfectives other than antibiotics, Antifungal,
antimycobacterials-
Antiprotozoal
General
Pharmacognosy: Definition, Historical background, Classification of
Crude drugs, Scope of
Pharmacognosy, Collection, Cultivation (including Tissue culture
method) and
Preparation for the market of Medicinal Plants. Marine Products.
Phytochemistry :
Chemical constituents of medicinal plants (Alkaloids, Glycosides,
Steroids, Plant
Pigments, Proteins, Enzymes, Carbohydrates, Lipids, Tannins,
Terpenoids,
Flavonoids, etc.) Biogenesis of Natural Products: like Carbohydrates,
Glycosides,
Alkaloids, Lipids, Terpenoids, Tannins, etc. Various conventional and
modern techniques
used in extraction and isolation of crude drugs and phytochemicals.
Phase Transfer
Catalysis, Raw materials for general manufacture in Pharmaceutical
Industry.,
Manufacturing plant; Including safety devices etc., Types of
reactors and their
configuration, typical reactor assemblies and characteristics - Emerging
unit processes.
Synthesis of 15 drugs
in the classes of anti – infective, antihistaminic, CNS drugs,
CVS drugs and NSAIDS
with aromatic
Synthesis of vitamins
and peptide.
Books:
1. Pharmaceutical
Dosage Forms And Drug Delivery Systems, Ansel, Philadelphia,
Fea and Febiger, 1985
2. Introduction to
Pharmaceutical Dosage Forms Ansel, Henry Kimpton Publishers,
London.
3. Pharmaceutics: The
Science of Dosage Form Design Aulton, New Delhi, B.I.
Naverly Pvt. Ltd.,
1995
4. Modern
Pharmaceutics G.S. Banker New York, Marcel Dekker1990
5. Bentely’s Textbook
of Pharmaceutics Rawlins Cassell Ltd, London
6. Fundamentals of
Pharmacy Blome H.E. Philadelphia, Fea and Febiger, 1985
7. Fundamentals of
Pharmacy Blome H.E. Philadelphia, Fea and Febiger, 1985
8. Pharmaceutial
Production Facilities: Design and Applications G.C.Cole
9. New York Ellis
Horwood 1990
10. Husa’s
Pharmaceutical Dispensing Martin E.W. Easton Mack Pub. Co. 1971
11. Transdermal
Delivery of Drugs A.Kydonieus Florida, CRC Press, 1987
12. Transdermal
Controlled System Medications Y.W.Chien, New York, Marcel
Dekker 1987
13. Quantitative
Pharmaceutical Chemistry, Glann L. Jenkins, Adelbert M. (VI
Edition) McGraw-Hill
Books Company
14. Text Book of
Pharmaceutical Analysis, Kenneth A., Connors, A Willey
Interscience
Publication, USA
15. Wolfgang Aehle, “
Enzymes in Industry Production and Applications” Wiley
VCH Publication, 2003
16. Heinrich Klefenz,
”Industrial Pharmaceutical Biotechnology” Wiley-VCH
Publication, 2002.
17. T. Scheper,
“Process Integration in Biochemical Engineering” Springer
Publication, 2003.
18. Oligan Repic,
“Principles of Research and Chemical Development in the
Pharmaceutical
Industry Wiley Interscience 1998.
19. Romano Di Fabio,
“From Bench to Market the Evolution Chemical
Synthesis” Oxford
University Press, 2000
5.
ELECTIVE – I
OPTIMIZATION
TECHNIQUE IN CHEMICAL ENGINEERING
Examination
Lectures
: - 3 hrs per week Theory : 100
Practical
/Oral : - Practical : - -
Internal
: -
External
: -
Section
I
Introduction, Scope,
Function of single variables, Methods of optimum point
search and
applications their to batch distillation column, Ammonia synthesis etc.,
Multivariable
functions. Direct search methods, First order, Second order methods,
Application to
flashing of multicomponent mixture, Equilibrium composition of
products of chemical
reactions, Heat conduction etc. Constrained optima, Equality
constraints,
Inequality constraints.
Section
II
Linear programming,
Non – linear programming, Geometric programming,
Applications to
extraction and solvent recovery systems, Condenser design, Complex
chemical equilibria,
Dynamic programming and its applications, Distillation,
variational methods
and its applications.
References:
1. Optimization of
Chemical Processes – T.F. Edgar and Hemmelblue, McGraw
Hill Book Company.
2. Optimization –
Theory and its Applications, S. R. Rao.
3. C.L. Smith, R. N.
Pike, P. W. Muralli, Formulation and Optimization of
Mathematical Model,
International Textbook Co., Perrylvania – 1970.
6.
SEMINAR
Examination
Lectures:
- Theory: -
Practical
/Oral
Practical:
2 hrs/ batch Internal: 25
External:
-
Students will be
required to prepare one review report (seminar) on selected topics in
Chemical Engineering
and should deliver one seminar (30 minute) and submit in the
form of a standard
typed format to the staff member/guide
Student
should submit title of seminar with min 10 reference in the first week of the
Semester
The
prepared report should contain some major points-
(i) Introduction:
Maximum 2 pages
(ii) Review of
literature (including figures): 10-12 pages
(iii) Analysis of
literature: students should make analysis of literature available:
4-5 pages.
(iv) Comments on the
analysis : based on method used in literature/ suggestion
Evaluation
based on above points as-
(i) Students will be
required to make an oral presentation of the seminar report
min 20 PPT slide.
(ii) Students should
deliver the seminar in front of students and internal judge
committee evaluates
the performance.
(iii) Asking and
answering questions during the seminars.
(iv) Seminar reports
The
staff member/members shall guide the students in :
1. Selecting the
seminar topic.
2. Information
retrieval (literature survey)
a) Source of
Information i.e. names of the journals, reports, books etc.
b) Searching for the
information i.e. referring to chemical abstracts etc.
3. Preparing the
seminar report
4. Delivering the
seminar
7.
COMPREHENSIVE TEST
Examination
Lectures:
- - Theory: -
Practical
/Oral
Practical:
2 hrs./ Week Internal: 50
External:
-
The objectives of the
comprehensive test are to assess the overall level of proficiency and
the scholastic
attainment of the student in the various subject’s studies during the degree
course by conducting
weekly tests. The Staff member/members shall guide the student in
preparing for the
weekly tests, which consists mainly bit questions and small problems.
The term work
assessment shall be based on the performance of the student in the test.
Minimum 10 tests
should be conducted. Syllabus of various subjects for the test is:
1.
Mathematics: -
Linear Algebra,
Calculus, Differential equations, Complex variables, Probability and
Statistics, Numerical
Methods
2.
Mechanical Operation: -
Size reduction and
size separation; free and hindered settling; centrifuge and cyclones;
thickening and
classification, filtration, mixing and agitation; conveying of solids.
3. Fluid
Mechanics: -
Fluid statics,
Newtonian and non-Newtonian fluids, Bernoulli equation, Macroscopic
friction factors,
energy balance, dimensional analysis, shell balances, flow through
pipeline systems,
flow meters, pumps and compressors, packed and fluidized beds,
elementary boundary
layer theory
4.
Heat Transfer: -
Conduction,
convection and radiation, heat transfer coefficients, steady and unsteady heat
conduction, boiling,
condensation and evaporation; types of heat exchangers and
evaporators and their
design.
5.
Process Calculations: -
Laws of conservation
of mass and energy; use of tie components; recycle, bypass and
purge calculations;
degree of freedom analysis.
6.
Mass Transfer: -
Fick’s laws,
molecular diffusion in fluids, mass transfer coefficients, film, penetration
and surface renewal
theories; momentum, heat and mass transfer analogies; stage wise
and continuous
contacting and stage efficiencies; HTU & NTU concepts design and
operation of
equipment for distillation, absorption, leaching, liquid-liquid extraction,
drying,
humidification, dehumidification and adsorption.
7.
Chemical Reaction Engineering: -
Theories of reaction
rates; kinetics of homogeneous reactions, interpretation of kinetic
data, single and
multiple reactions in ideal reactors, non-ideal reactors; residence time
distribution, single
parameter model; non-isothermal reactors; kinetics of heterogeneous
catalytic reactions;
diffusion effects in catalysis.
8.
Instrumentation & Process Control: -
Measurement of
process variables; sensors, transducers and their dynamics, transfer
functions and dynamic
responses of simple systems, process reaction curve, controller
modes (P, PI, and
PID); control valves; analysis of closed loop systems including
stability, frequency
response and controller tuning, cascade, feed forward control.
9.
Chemical Technology: -
Inorganic chemical
industries; sulfuric acid, NaOH, fertilizers (Ammonia, Urea, SSP and
TSP); natural
products industries (Pulp and Paper, Sugar, Oil, and Fats); petroleum
refining and petrochemicals;
polymerization industries; polyethylene, polypropylene,
PVC and polyester
synthetic fibers.
10.
Plant Design & Economics: -
Process design and
sizing of chemical engineering equipment such as compressors, heat
exchangers,
multistage contactors; principles of process economics and cost estimation
including total
annualized cost, cost indexes, rate of return, payback period, discounted
cash flow,
optimization in design.
Question
Pattern for the test (50 Marks, Time Duration: 2 hr): -
1. 15 objective
questions of 1 mark each
2. 15 problems of 2
marks each
3. 5 objective (aptitude)
questions of 1 mark each
References:
-
1. A
text book of Applied Mathematics: Vol. I, II and III by J. N. Wartikar & P.
N.
Wartikar, Vidyarthi
Griha Prakashan, Pune.
2. Mc Cabe W.L. and
Smith J.C. ‘Unit operations of Chemical Engg.’ VII ed.
Mcgraw Hill Book Co.,
International ed. 1993
3. Himmelblau D.M.,
“Basic Principles and Calculations in Chemical Engineering”,
Sixth Edition,
Prentice-Hall of India Pvt. Ltd., 2004.
4. J.M. Smith and
H.C. Van Ness, “Introduction to Chemical Engg.”,
Thermodynamics 6th
Edition, International student edition, McGraw Hill
publication.
5. Eckman D.P.
“Industrial Instrumentation”, Willey Eastern Ltd, New Delhi, 1984.
6. Robert E. Treybal,
“Mass Transfer Operations”l, Third Edition, McGraw Hill,
1980.
7. Stephanopoulos G
,“Chemical Process Control and introduction to theory and
practice”
8. S.H. Fogler,”
Elements of Chemical Reaction Engineering”, PHI, 3rd Edition.
9. George T. Austin,
“Shreve's Chemical Process Industries”, 5th edn. , McGraw
Hill Book
Company,1985.
10. M.S. Peters &
K.D.Timmerhaus, “Plant Design and Economics for Chemical
Engineers”, 3rd
edition, McGraw Hill International Book Co., 1980.
8.INDUSTRIAL
TRAINING
Examination
Lectures:
-- Theory: -
Practical
/Oral
Practical:
-- Internal: 25
External: -
In-Plant
Training Evaluation:
The students are
required to undergo at least four weeks of In-plant training during
summer vacation
between T.E. Part -II and B.E. Part –I. They will be required to submit
a written report on
their In-plant training.
The report should
consist of
(i) Major products of
the company
(ii) Plant
description
(iii) General plant
layout
(iv) Processes for
Major Products (no confidential proprietary information may be
included)
(v) Chemistry of
processes studied (in case of chemical manufacture) based on
Journal papers,
Patents, Books, etc.
(vi) Safety and
Health (Material Safety Data Sheets, Safety Policy)
(vii) Environmental
Protection (measures used and general description of the processes
and facilities used)
(viii) Standards and
compliance thereof (ISO 9000, ISO 14000, OHSAS 18000, etc.)
(ix) Three Major
Equipment – description with sketch (no detailed drawing to be
given: just a sketch
with major dimensions, nozzle location and dimensions
thereof)
(x) Heat Exchangers:
total number and types, Pumps and Compressors: total number
and types,
(xi) Improvements
proposed by the student, for example, Power savings for pumps,
blowers, compressors,
etc. Cycle time reduction in case of batch processes, Waste
heat recovery, Waste
solvent recovery, Product quality improvement, Any project
assigned to you by
the company (title, a short description, results and conclusions)
Students will present
their work before a panel of teachers in the Institute which will be
assessed internally
at B.E. Part -I. The report would carry 50% weightage and the
presentation would
carry 50% weigh
In case, due to
illness or any other reasonable problems the student fails to undergo above
said training, he may
be allowed to visit/ tour some industries and submit a report.
9.
Project Work
Examination
Lectures:
-- Theory: -
Practical
/Oral
Practical:
4hrs./Week Internal: 50
External:
--
Types
And Selection of Projects :
The students are
required to carry out one of the following projects.
1. Processes based
Project : Manufacture process of a product.
2. Equipment based
Project : Detailed design and fabrication of the
equipment for a given
capacity and results after experimentation.
3. Experimental based
Project : Experimental investigation of basic or
applied research
problem.
4. Industrial
Problems : Any problem or project directly related to
existing plants for
modification of process or equipment or regarding
pollution control and
energy conservation etc.
5. Process Simulation
/ Software based project.
Objectives:
To work in a team in
a planned manner on a chosen engineering topic based on the
knowledge gained
throughout the engineering programme.
Contents:
Three to four
students will be allotted project in a group. The project is to be completed
in two parts: Project
I in Semester VII and Project II in Semester VIII. Each project will
have one guide from
the faculty. Students may be encouraged to choose a co guide from
the industry,
wherever possible.
A proper planning of
the project work or research institute is expected. The project group
should prepare
activity chart and submit the same along with the reports for part I and
part II. The group
should also submit and present the work completed in semester I in an
appropriate format.
The actual contents of the project report may be decided in
consultation with the
project guide.
Students are expected
to carry out an in-depth literature survey based on
chemical/engineering
abstracts, national/international journals using online/print media.
Proposed work
synopsis / abstract approved by guide should be submitted within two
month of the course
started and approved by the guide.
Students will be
required to prepare a critical review of selected projects in Chemical
Engineering and
allied subjects and submit in the form of a standard typed report.
Typically, the report
should contain and will be evaluated based on the following points:
(i) Introduction: 2
pages maximum,
(ii) Exhaustive
review of literature, Critical analysis of the literature and comments on the
analysis (including
figures): 12 to 15 pages: 50% weightage
(iii) Kinetics &
thermodynamics study, material balance, energy balance,
experimentation /
detailed design of equipments - 12 to15 pages: 50% weightage.
The critical analysis
of literature should include the following points: Is the project
technically correct?
Are assumptions reasonable; is the reasoning logical? If you think it
is not, specify what
you think is incorrect and suggest the correct approach. Are the
methods used in the
literature appropriate? Are there any internal contradictions or
computational errors
and are there any loopholes in the observations? If so, please
explain it. Critical
analysis of papers should also contain quantitative comparison of
observations, results
and conclusion amongst the various papers. Each student will also
be required to make
an oral presentation of the review. Weightage would be 40% for
presentation and 60%
for the report. Additional details are given in table 1.
Half part of project
work should be complete within the first semester. Term work consist
a reports of 30 to 40
pages which has to be submitted at the end of VII semester along
with the presentation
before faculty and students.
The report should be
prepared using the Times Roman font (size 12) using 1.5 spacing
leaving 1 inch margin
on all sides producing approximately 29 lines per page. The report
is to be typed on one
side of the paper and need not be bound in a hard cover binding.
Figures and tables
should be shown as a part of the running text. Each figure should be
drawn inside a
rectangular box of 12 cm width and 10 cm height. The figures must be
sufficiently clear
and hand drawn figures will be acceptable. Particular care must be taken
if a figure is
photocopied from source.
Each figure must have
a sequence number and caption below. Each table must have a
sequence number and
title at the top. The report must be precise. All important topic
should be given due
considerations.
The total number of
pages, including tables, figures and references should not exceed 40.
Chapters or
subsections need be started on new pages, while getting the report typed.
The activity chart
should be completed as per the following stages:
Table
1 – Activity Chart
General
Project
Sr. no. Stage
Activity /Week No. Period
1 Synopsis / Abstract
2 Detailed Literature
Survey
3 Process and Site
selection
4 Block Diagram
5 Kinetics &
thermodynamics
feasibility
6 Material &
Energy balance
7 Detail design of
equipments /
methodology of
Experimentation
SHIVAJI UNIVERSITY, KOLHAPUR
(INTRODUCED FROM JUNE, 2010)
Revised syllabus structure of Chemical
Engineering
B.E. Chemical Part – II
1. CHEMICAL PROCESSES AND GREEN TECHNOLOGY
Examination
Lectures
: - 4 hrs per week Theory : 100
Practical
/Oral
Practical
: 2 hrs /batch Internal : 25
External
: 25
Section
– I
1.
Explosives: Types of explosives, explosive characteristic, Industrial
explosives,
propellants, rockets,
missiles, pyrotechnics, matches, toxic chemical weapons.
2.
Food industries: Types of food processing, preservation methods, Food
byproducts.
3.Pulp
and paper industries: Manufacturing of pulp, Manufacturing of paper,
Structural boards
4.Plastic
industries: Raw materials, General polymerization processes,
Manufacturing
processes, Compounding and moulding operation.
5
Pharmaceutical industries: Classification of pharmaceutical
products.
Manufacture of
antibiotics, Isolates from plant and animals, vitamins.
Section
– II
6.
Green Chemistry: An Overview
Introduction,
underlying philosophy and focus, Twelve principles of green chemistry
7.
Ecological Threats & Green Chemistry
The Greenhouse
Effect, Climate Change, photochemical smog, Pragmatic Green
Chemistry Challenges,
Old Technology vis-à-vis Green Technology : Suitable examples
to understand
comparative advantage of Green Technology over Old one, Renewable
resources, Process
intensification , Carbon credits .
8.
Green Chemistry & Nonconventional Fuels
Green chemistry in
batteries, production and recycling, Fuel cell and electric vehicles,
Solar energy and
hydrogen production, biodiesel, bio-hydrogen
9.
Green Chemistry & Sustainable development
Esterification:
transesterification, autogeneous pressure of methanol, transesterification
under supercritical
conditions
Optimisation:
catalyst concentration, methanol to oil ratio, reaction temperature, reaction
time
Best practices in
Green Chemistry for sustainable development with suitable examples
List
of practicals:
1. Preparation of azo
dye
2. Preparation of
soap
3. Preparation of
green, yellow, blue pigments
4. Preparation of
nitrobenzene.
5. Glucose Estimation
6. Preparation of
drug aspirin
Text
Book:
1. George T. Austin,
“Shreve's Chemical Process Industries”,5th edn., McGraw Hill
Book Company, 1985.
2. Paul T. Anastaj;
“Green Chemistry – Theory and Practice”
3. Albert S. Matlack
; “Introduction to Green Chemistry”
References:
1. S.D. Shukla, G.N.
Pandey. “A Text book of Chemical Technology”, 3rd
Edition.
2. C.E. Dryden,
“Outlines of Chemical Technology”, Affiliated East-West Press,
1973.
3. D. Venkteshwaralu,
“Chemical Technology”, I & III manuals of Chemical
Technology Chemical
Engg. Ed. Dev. III Madras, 1977.
4. Faith, “Industrial
Chemicals”
5. Rogers,
“Industrial Chemistry”.
6.Anastas, P.;
Warner, J. Green Chemistry: Theory and Practice; Oxford University
Press: London, 1998.
7.Zimmerman, J.B.;
Anastas, P.T. “The 12 Principles of Green Engineering as a
Foundation for
Sustainability” in Sustainability Science and Engineering: Principles. Ed.
Martin Abraham, Elsevier
Science. available 2005.
8.Anastas, P.;
Zimmerman, J. “Design through the Twelve Principles of Green
Engineering,”
Environmental Science and Technology, 37, 94A – 101A, 2003.
2.
TRANSPORT PHENOMENA
Lectures:
3 hrs per week Examination:
Tutorial
: 1 Theory: 100
Practical
/Oral:
Internal: 25
Section
I
1.
Viscosity and the mechanism of momentum transport: (2 Hrs.)
Newton’s law of
viscosity, non Newtonian fluids, pressure & temperature dependence of
viscosity, estimation
of viscosity from critical properties.
2.
Velocity distribution in laminar flow: (4 Hrs.)
Shell momentum
balances, boundary conditions, flow of a falling film, flow through a
circular tube, flow
through annular, creeping flow along a solid sphere.
3.
The equations of change for isothermal systems: (3 Hrs.)
Time derivatives, the
equation of continuity, the equation of motion, the equations of
change in
curvilinear, co-ordinates, use of the equations of change to set up steady flow
problems.
4.
Velocity distributions: (2 Hrs.)
With more than one
independent variable, unsteady viscous flow, flow near a wall
suddenly set in
motion.
5.
Inter phase transport in isothermal systems: (3 Hrs.)
Definition of
friction factors, friction factors for flow in tubes, friction factors for flow
around spheres,
friction factors for packed column.
6.
Macroscopic balances for isothermal systems: (3 Hrs.)
The Macroscopic mass
balance, the macroscopic mechanical energy balances, estimation
of friction loss, Use
of macroscopic balances to set up steady flow problems.
7.
Thermal conductivity and the mechanism of energy transport: (3 Hrs.)
Fourier's law of heat
conduction, temperature and pressure dependence of thermal
conductivity in gases
and liquids, theory of thermal conductivity of gases at low density.
Section
II
8.
Temperature distributions in solids and in laminar flow: (4 Hrs.)
Shell energy balance,
boundary conditions, Heat conduction with an electrical heat
source, Heat
conduction in cooling fins, heat conduction with exothermic reactions.
9.
Temperature distributions with more than one independent variables: (2 Hrs.)
Unsteady state heat
conduction in solids, Boundary layer theory.
10.
Interphase Transport in Non isothermal Systems: (3 Hrs.)
Definition of heat
transfer coefficients, Heat transfer coefficient for forced convection in
tubes, Heat transfer
coefficient for forced convection around submerged objects, through
packed beds, Heat
transfer coefficient for free and mixed convection, Heat transfer
coefficient for
condensation of pure vapors.
11.
Macroscopic balances for Non-isothermal systems: (3 Hrs.)
The macroscopic
energy balance, the macroscopic mechanical energy balance, use of the
macroscopic balances
for solving steady state problems, Summery of macroscopic
balances of pure
fluids, Solution to the following cases, Parallel counter flow heat
exchanger, The
cooling of an ideal gas.
12.
Diffusivity and the mechanism of mass transports: (2 Hrs.)
Definitions of
concentrations, velocities & mass fluxes, Fick's law of diffusion,
Temperature &
pressure dependence of mass diffusivity, Maxwell’s law of diffusion.
13.
Concentration distributions in solids and in a laminar flow: (3 Hrs.)
Shell mass balance,
boundary conditions, diffusion through a stagnant gas film, Diffusion
with heterogeneous
chemical reaction, Diffusion with homogeneous chemical reaction,
Diffusion in to a
falling liquid film.
14.
Introduction to the Computational Fluid Dynamics: (3 Hrs.)
Philosophy of
computational fluid dynamics, conservation principles of mass, energy,
and momentum, simplified
flow models such as incompressible, in viscid, potential and
creeping flows,
classification of flows, Grid Generation, Structured and unstructured
grids, choice of
grid, general transformation of equations, some modern developments in
grid generation in
solving engineering problems.
Term
Work:-
Minimum of eight
assignments should be given to students. 50 % of assignments should
be numerical
problems.
Text
Book:
1. R.B. Bird, W.E.
Stewart and E.N. Lightfoot, “Transport Phenomena”, John
Wiley & Sons, Inc,
New York.
References:
1. C.O. Bennett, J.E.
Mayers, “Momentum, Heat & Mass transfer”, 3rd Edn.,McGraw
Hill, Chemical
Engineering Series,1985.
2. Alan S. Foust,
Leonard A. Wenzel, Curtisw Clump, Louis Maus,L Bryce Andersen
“Principles of Unit
Operations”,2nd edn.,McGraw Hill, 1985.
3. C.J. Geankoplis
" Transport Processes Momentum And Mass" Bacon Inc. 1983.
4. L.E. Sissom &
D.R. Ritts ,"Elements of Transport Phenomena" McGraw Hill, J.R.
Welty, R.E. Wilson
& C.E. Wicks, " Fundamentals of momentum, heat & mass
transfer"
2nd edn. John Wiley,
New York 1973.
5. Anderson Jr J. D.,
“Computational Fluid Dynamics: The Basics with Applications”,
McGraw Hill.1995
6. Muralidhar
K. and Sundararajan T., “Computational Fluid Flow and Heat Transfer”,
Narosa Publishing House.
2003
7. Ranade V. V,
“Computation Flow Modeling for Chemical Reactor Engineering”,
Academic Press. 2002
3.
PROCESS ECONOMICS AND PROJECT ENGINEERING (PEPE)
(New
Revised)
Examination
Lectures
: - 4 hrs per week Theory : 100
Practical
/Oral
Practical
: - Internal : 25
External
: -
Section
– I
1.
Introduction.
2.
General design considerations.
3.
Process Design Development
4.
Flow sheet Synthesis and Development
5.
Cost and asset accounting.
6.
Analysis of Cost estimation.
7.
Interest, Time value of Money, Taxes and Fixed Charges.
8.
Profitability, alternative investments and replacements.
9.
Optimum design and Design strategy.
10.
Written and Oral Design Reports.
Section
– II
11.Process
development and commercialization—Introduction, Exploratory research
process development,
development for final process design, development of established
processes,
12.ProcessLicensing-Licensingprinciples,Licenseagreement,Agreement
implementation.
13.Selection
of contractor scope and contract types – Introduction, Detailing of
scope
of work, Factors in
selecting scope of work, detailing of contract types, Factors in
selecting type of
contract.
14.Plant
Startup – Introduction, Organization of startup, Budget for startup,
Information
centre, Planning and
schedules, Log sheets and calculations, Training personnel, Planning
of testing and
preoperational procedures, Initial startup, Operating the plant.
15.
Project conception and definition : Selection of plant capacity,
Causes for time and
cost over runs of a
Project, Process Optimization, Selection of Alternative Processes
Equipment.
16.
Project Engineering : Management and Organization, Project
Planning, Scheduling
and Controlling , Use
of bar and milestone chart, PERT/ CPM - Introduction, Activity
sequencing, Network building,
Time estimates, Critical path calculations.
Text
Books:
1. M.S. Peters &
K.D.Timmerhaus, “Plant Design and Economics for Chemical
Engineers”, 5th edition,
McGraw Hill International Book Co.,2003.
2. Lundu, “The
Chemical Plant”.
3. J.M. Coulson &
J.F Richardson, “Chemical Engineering”, Vol.6, 5th edition
Pergamon
& ELES, 2003.
4. Modes J. &
Philips, “Project Engineering with C.P.M. & PERT”, Rein hold.
5. Srinath L.S. “PERT
& C.P.M. Principles and Applications”3rd edition,
East-West
Publication 2003.
6. GAEL D. ULRICH, “A
Guide to Chemical Engineering Process Design and E” John
Wiley & Sons,
1984.
7. N. D. Vohra,
“Quantitative Techniques in Management”, 2nd edition
Tata McGraw Hill
Publishing company
Ltd., New Delhi 2005.
References:
1. Rase, H.F. Barrow,
M.H. “Project Engineering of Process Plants”, John Wiley.
2. Schewayer, H.E.
“Process Engineering Economics”, McGraw Hill
3. Chilton, C.H.,
“Cost Engineering in Process Industries”, McGraw Hill
4. Happel J. Jordan,
D.G. “Chemical Process Economics”.
5. Tacmin A,J. Blank
L.T. “Engineering Economy”
6. V.W. Wni. &
A.W. Hankins, “Technical Economics for Chemical Engineers”
(AICHE)1971.
4.ELECTIVE
– II
1.
BIO-CHEMICAL ENGINEERING
Examination
Lectures
: - 4 hrs per week Theory : 100
Practical
/Oral Practical :-
Internal
: --
External
: --
1. Introduction.
Biochemical
Engineering – the interaction of two disciplines, Comparison of
chemical and
biochemical process, Role of biochemical engineers in development of
modern formation
industry, Future development, Applications of engineering
advances.
2. Chemical
Activities of Microorganisms.
Biological oxidation
and transfer of energy, Pathways to provide energy and
metabolism for
growth, EMP – pathway, HMP – pathway, Anaerobic metabolism of
pyravate, TCA cycle,
Yield of cells, Production of amino acids, Nucleotides,
Antibiotics.
3. The kinetics of
enzyme catalyzed reactions.
Simple enzyme
kinetics with one and two substrates, Determination of elementary step
rate constant,
Substrate activation and inhibitation, Multiple substrate,Modulation and
regulation of enzyme
activity, Enzyme deactivation, Effect of PH, Temperature,
inhibitors on enzyme
activity.
4. Kinetics of
Substrate Utilization.
Ideal reactors for
kinetics measurement, Kinetics of balanced growth, Transient
growth kinetics,
Structured kinetics model, Product formation kinetics.
5. Transport
phenomena in microbial systems.
Gas liquid mass
transfer in cellular system, Determination of OTR, mass transfer
freely rising or
falling bodies, Forced convection mass transfer, Estimation of
overall kla, Heat
transfer correlation, Mass transfer and microbial respiration,
Theories of
diffusional mass transfer.
6. Design and
analysis of biological reactors.
Ideal bioreactors,
Reactor dynamics, Microbial dynamics in chemostat culture, Mass
balance in a series
vessel, Mass balance with recycle, Comparison between batch and
continuous
cultivation, Sterilization reactors, Animal and plant cell reactor technology,
Examples of design
calculations.Design and construction of fermenter, Multiphase
reactors.
7. Translation of
laboratory culture results to plant operations, Scale down, Data
translation,
Performance of shaker flask, Fermentation technology, Design and
operation of typical
aseptic, Aerobial fermentation process.
8. Introduction of
advanced topics such as.
Bioprocess
simulation, Molecular modeling for protein synthesis and drug design,
Protein engineering,
Manufacturing process for typical pharmaceutical products.
References:
1. J.E. Bailley and
D.F.Olis, “Bio-chemical Engineering Fundamentals”, McGraw
Hill, New York, 1977.
2. S.Aiba, A.E.
Humphrey and N.R. MHH, “Bio-chemical Engineering”, Second
Edn. Academic Press,
1973.
3. F.C. Web,
“Biochemical Engg.” Van Nostrand, 1964.
4. B. Atkinson,
“Biochemical Reactors”, Plon Ltd., 1974.
5. Willy Berg,
“Advanced Bio-Chemical Engineering”
6. Desai A.V.,
“Bio-energy”, Willey Eastern Ltd. New Delhi,1990.
7. Lehninger A.L., “
Bio-Chemistry” ,Worth Publication, Inc.,New York, 1972.
8. Bungay
H.R.,Belfort G., “Advanced Bio-Chemical Engineering” ,John Willey
And Sons,New York,
1987.
4.
ELECTIVE – II
2.
PETROCHEMICAL TECHNOLOGY
Lectures:
4 hrs per week Examination
Theory:
100
Practical/Oral
Internal: -
External:
-
Section
I
1.
General Introduction: (5 Hrs.)
Definition of
petrochemicals, history of petrochemical industry, development of petrochemical
industry in India,
product profile of petrochemicals, economics of petrochemical industry, general
cost considerations,
indigenous technology v/s foreign know-how, economics of R&D, sources of
petrochemicals,
natural gas & petroleum, classification of petrochemicals.
2.
Raw Materials: (4 Hrs.)
Organic chemicals,
coal, biomass petroleum, etc.
3.
Chemicals from Methanol & Synthesis gas: (4 Hrs.)
Steam reforming,
Oxo-Products, Methanol, Formaldehyde, Carbon-di-sulphide, Hydrogen cyanide.
4.
Chemicals from Ethane, Ethylene & Acetylene: (4 Hrs.)
Synthetic Ethanol,
Acetaldehyde, Acetic acid, Vinyl acetate, Ethylene oxide, Ethylene glycols,
Acrylonitrile,
Ethanol amines.
5.
Chemicals from Propane & Propylene: (4 Hrs.)
Isopropanol, Acetone,
Glycerol, Propylene oxide, Propylene Glycols, Isoprene, Cumene.
Section
II
6.
Chemicals from Butanes & Pentanes: (4 Hrs.)
Butadiene, Butone
epoxides & Butanol amines, Butyl acetate, Methyl-Ethyl Ketone, MTBE, TAME.
7.
Chemicals from aromatics: (5Hrs.)
BHC, Nitrobenzene,
Do-decyl benzene, Benzoic acid, Nitrotolune, Pthalic anhydride, Isopthalic
acid, TPA & DMT,
Maleic anhydride, Adipic acid, Hexamethylene diamine, Aniline, Caprolactum.
8.Polymers:
(4 Hrs.)
Polymers, elastomers,
synthetic fibers, PVC, Nylon & Polyesters.
9.
Future of Petrochemicals: (6Hrs.)
Integrated
Petrochemical complex, Energy crises in Petrochemical industry, Natural gas as
Petrochemical
feedstock, Import of heavy feedstock on Petrochemicals, Ecology & energy
crises,
Coal as an
alternative to oil, Synthetic fuels, Trends in Petrochemical Industry.
NOTE:
The journals such as Hydrocarbon Processing, Chemical engg.
Progress must be used for the latest technologies.
Text
Books:
1. B.K.
Bhasker Rao, “A Text on Petrochemicals”2nd Edition,
Khanna publishers, 1996.
2. Sukumar
Maiti, “Introduction to Petrochemicals” Oxford & IBH publishing Co. Pvt.
Ltd., 1991.
3. Ram
Prasad, “Petroleum Refinery Technology”, Khanna publications.
References:
1. A.V.G. Halm, “The
Petrochemical Industry”, McGraw Hill 1970.
2. A.L. Waddams,
“Chemicals from Petroleum”, Chemical publishing Co.
3. Astle M.J., “The
Chemistry of Petrochemicals”, Reinhold.
4. C.E. Dryden,
“Outlines of Chemical Technology”, Affiliated East-West Press, 1973.
5. Faith Keys,
“Industrial Chemicals”.
4.
ELECTIVE – II
3. COMPUTER
AIDED DESIGN
Examination
Lectures
: - 4 hrs per week Theory : 100
Practical
/Oral Practical : --
Internal
: --
External
: --
1. Central processors
: Introduction to central processors; Historical
approach, Analog
computers; Digital Computers; The Hardware bus; Shift
Register; Output
Buffer; Digital logic; CPU, ALU, Computer System
Architecture; I/O ;
Remote Access; Performance.
2. Data storage :
Role of Storage devices; Main memory; Backing Storage;
Need for memory
mapping; Virtual addressing, Paging.
3. Alpha numeric and
graphic I/O : Batch and Interactive processing; Data
input devices; Data
Output devices; Combination at I/O devices; I/O
control devices;
Graphic computer terminal, Graphic display; Graphics
terminals; Graphic
Display, Graphics terminals; Plotters; Printers.
4. Basic software :
Operating System and executive; Operating system
function; Models of
operation; Batch Operation; Time sharing; Real time
Operation; Transaction
Processing; File management system; Logging on
and off, Editors;
Computers; Data tables; Graphic software.
5. Properties
evaluation : Concepts of CAD Physical properties of compounds
Thermodynamic
properties at gases and binary mixtures; Viscosity;
Vapour pressure,
latent heat, bubble point and dew point calculation;
Phase equilibria,
Vapour -liquid equilibria.
6. Equipment design :
Computer aided design of reactors; evaporators,
absorption column,
distillation column and crystallizes, Heat transfer
equipment like heat
exchangers, furnaces etc, Pumps, Piping, Pressure
drop calculations;
Mass and Energy balance.
7. Flow sheet
simulation : Process flow sheet simulation; Process and
information matrix,
Recycle calculation sequence; Materials and Energy
balance computation
using modular approach; Process analysis, Process
variables, selection,
Equipment selection.
8. Dynamic simulation
: Dynamic simulation of Reactors, distillation
column, Absorbers,
evaporators and crystallizes, introduction to
simulation packages
like GPSS, CSMP.
References:
1. M.P. Groover, E.W.
Timmers, “Computer Aided Design and Manufacturing”,
Prentice Hall of
India Pvt. Ltd., New Delhi, 1985.
2. L. Nashelsky,
“Introduction to Digital Technology”, John Wiley and Sons,
New York, 1983.
3. E.J. Henley, and
F.M. Rusen, “Material and Energy Balance Computations”,
John Wiley, New York,
1969.
4. E.D. Oliver,
“Diffusional Separation Process”, John Wiley and Sons, New
York, 1966.
5. B.D. Smith,
“Design of Equilibrium Stage Processes”, McGraw Hill Book Co.
New York, 1963.
6. Crowe, C.M. et.
al., “Chemical plant simulation-An Introduction to
Computer aided
steady-state process analysis”, Prentice Hall, 1971.
7. Franks, R.G.E.,
“Modelling and simulation in Chemical Engineering”, Wiley
Inter Science, 1972.
8. Holland C.D.
“Fundamentals and modelling of separation processes”,
absorption,
Distillatkion, evaporation and extractikon, Prentice Hall, 1975.
9. Afgan, N.H. and
Schlunder, C.V., “Heat Exchangers-design and theory
source book” Scripta
Book, Washington, 1974.
10. Chussain, A.
“Chemical Process simulation”, Wiley eastern, 1986.
11. Wester Berg, A.W.
et.al. "Process Flow Sheeting", Cambridge UniversityPress,
1979.
12. Myers, A.L. and
Seeden, W.D. “Introduction to Chemical Engineering and
Computer
Calculations” Prentice Hall, 1976.
13. Prausnitz, S.,
“Computer calculaltions in Multi Component vapour
liquidequilibria”
Prentice Hall, 1980.
14. Welison, C. and
Hobson P.M., “Combination for Process Engineers”,
Leonard Hill, 1973.
4. Elective
– II
4. DISTILLATION
Examination
Lectures
: - 4 hrs per week Theory : 100
Practical
/Oral Practical : - -
Internal
: -
External
: -
Thermodynamics of
equilibrium vapour liquid equilibria of ideal and non ideal
solutions- Binary and
Multi component systems. Correlation and prediction of VLE data
(Brief outlines
only). Principles of differential distillation and steam distillation.
Equilibrium Flash
vaporisation. Hydrocarbon water mixtures. Binary distillation
Determination of
minimum and total reflux calculations for the number of
equilibrium stages-
Analytical and graphical methods-problems with open steam
sidestreams. Multiple
feeds-batch columns multicomponent distillation: Preliminary
calculations -
selection of key components- Rigorouis calculations - Methods of
Sorel.
Lewis-Matheson, Thiele-Geddes and Short cut methods. Azeotropic and
extractive
Distillation. Separation of azeotrops selection of solvents and entrainers,
column design by
pseudo ternary and pseudo binary methods. Solvent recovery. Design
of distillation
equipment, plate and packed columns.
Books:
1. “Distillation”,
Van Winkle.
2. “Distillation
Design”, J. H. Kister
3. “Distillation
Operations”, J. H. Kister
4. “Design of
Equilibrium Stages”, B. D. Smith.
4.
Elective – II
5.
ENTERPRISE RESOURCE PLANNING
Examination
Lectures
: - 4 hrs per week Theory : 100
Practical
/Oral Practical : -
Internal
: -
External
: -
1. BPR in Indian
Context
2. ERP
Planning/Budgeting Process
3. ERP Implementation
Issues
4. Selecting ERP
product for your needs
5. Product
Presentations & Demonstration from World's Best ERP Products
6. like SAP R/3 etc.
7. Experiences of ERP
Live Sites
8. Post
Implementation Issues
4.
Elective – II
6.
ARTIFICIAL INTELLIGENCE IN PROCESS ENGINEERING
Examination
Lectures
: - 4 hrs per week Theory : 100
Practical
/Oral Practical : - -
Internal
: -
External
: -
Introduction –
History and relation of artificial intelligence (AI) to process engineering;
Knowledge
representation I – Predicate calculus and Semantic Networks; Search –
Forward / Backward,
Depth/breadth/best – first search; Production systems: History,
Components; Knowledge
representation II – Frames, Objects; Inexact Reasoning –
Introduction,
Bayesian certainty factors, Qualitative Physics, Casual Models –
Introduction,
Backward architecture; Expert Systems – Applications to industry;
Programming
Languages; Expert System Shells; Neural Nets – Introduction and
applications to
process engineering.
Books:
1. N.L. Nilsson,
“Problem Solving Methods in Artificial Intelligence”, McGraw
Hill, 1971.
2. T.E. Quantrille
and Y.A. Liu, “Artificial Intelligence in Chemical Engineering”,
Academic Press, 1991.
3. J. Zurada,
“Introduction to Artificial Neural Systems”, West Pub. Co. Ltd., St.
Paul, MN, 1992.
4. J. F. Davis, G.
Stephanopoulos and V. Venkatasubramanian, “Intelligent Systems
in Process
Engineering”, AIChE symposium Series, Vol. 92, 1996.
4.
Elective – II
7.
MEMBRANE SEPARATION PROCESS AND DESIGN
Examination
Lectures
: - 4 hrs per week Theory : 100
Practical
/Oral Practical : - -
Internal
: -
External
: -
1. Introduction:
Introduction to membrane processes, History, Definition of
membrane, importance,
processes.
2. Types of
membranes, Membrane processes and their applications, Porous
and solid membranes,
Osmosis, Micro – Filtration, Ultrafiltration, Nano
filtration, Reverse
Osmosis, Piezodialysis, Electrodialysis, Dialysis,
Membranes for gas
separation, Pervaporation, Applications to these
processes.
3. Liquid membranes,
Supported and unsupported liquid membranes,
Applications and
mathematical modeling.
4. Materials and
material properties, Polymers and effect of various
properties of
polymers such as Tg, Thermal, Chemical and mechanical
stability, Elastomers
and their properties, Inorganic membranes, Biological
membranes.
5. Characterization
of membranes: Characterization of porous
membranes,
Characterization of ionic membranes, Characterization of non
– ionic membranes.
6. Preparation of
synthetic membranes, Preparation of phase inversion
membranes,
Preparation techniques for immersion precipitation,
Preparation
techniques for composite membranes, Influence of various
parameters on
membrane morphology, Preparation of inorganic
membranes.
7. Transport
processes in membranes, Driving force, Transport through
porous membranes,
Transport through non porous membranes, Transport
in ion-exchange
membranes.
8. Polarization
phenomena and fouling concentration polarization,
Characteristic flux
behavior in pressure driven membrane operation,
Various models,
Temperature polarization, Membrane fouling, Methods to
reduce fouling.
9. Modules and
process design plate and frame, Spiral wound, Tubular,
Capillary, Hollow
fiber modules and their comparison, System design.
10. Membrane
reactors, Applications of membrane reactors in biotechnology
11. Economics and
feasibility of membrane technology, Comparison of
membrane technology
with separation techniques, Scope in future,
Current and existing
industrial applications.
Books:
1. Basic Principles
Of Membrane Technology, Marcel Mulder, Kluwer Academic
Publishers, 1997
2. Membrane
Separation Technology – E. J. Hoffma, Gulf Professional Publishing.
Reference:
3. Membrane Handbook
– Editors W. S. Winston Ho, K. K. Sirkar, Van Nostrand
Reinhold Publication.
4.
Elective – II
8.
NUCLEAR ENGINEERING
Examination
Lectures
: - 3 hrs per week Theory : 100
Practical
/Oral Practical : - -
Internal
: -
External
: -
Section
I
1. Nuclear Physics:
Atomic number and mass numbers, Isotopes, Nuclear energy
and nuclear forces,
Binding Energy, Nuclear Stability, Radioactivity, Nuclear
reactions,
Radioactive isotopes, Law of radioactivity, Interaction of radiation (alpha,
beta, gamma) with
matter, Interaction of neutrons with matter, Absorption radiative
capture,
Transmutation Fission, Cross section for nuclear reactions.
Fission process,
Mechanism of nuclear fission, fission cross section, fission
products, Basic radio
chemistry.
2. Reactor Physics:
Neutron balance, Neutron diffusion, Diffusion equation, and its
solution, Showing
down of neutrons, Showing down power and moderating ratio.
Reactor theory:
Multiplication factors, Four factor formula, One group critical
equation, Age,
Diffusion method, Non-leakage probabilities and effective
multiplication
factor, Multigroup diffusion theory, Homogeneous and heterogeneous
reactor systems, Time
dependent reactor behavior.
3. Nuclear Reactor
Engineering: Types of rectors, Ordinary water moderated
reactors (BWR, PWRO),
Heavy water cooled and moderated reactors, Gas cooled
reactors (HTGR, AGR),
Fast reactors design, Construction and control of nuclear
reactors.
Section
II
4. Heat transfer in
nuclear reactors: Heat transfer techniques in nuclear reactors,
Design and operation,
Thermal stresses, Reactor shielding.
5. Reactor materials:
Nuclear fuels, Moderators, Coolants, Reflectors and
structural materials.
6. Reprocessing:
Nuclear fuel cycle, Spent fuel characteristics, Reprocessing
techniques role of
solvent extraction in reprocessing.
7. Waste management
and radiation protection: Types of waste, Waste
management philosophy
and disposal, ICRP recommendations, Radiation hazards
and their prevention,
Radiation dose units.
8. Status of nuclear
technology in India: Indian nuclear power program, Nuclear
reactors in India,
India’s commitment to nuclear.
References:
1. S. Glasstone and
A. Seronske, “Nuclear Reactor Engineering”, Van Nostrand –
Reinhold, 1967
2. M. Bendict and
T.A. Pigtor, “Nuclear Chemical Engineering”, McGraw Hill,
1981.
3. L. C. Merrite,
“Basic Principles of Nuclear Science and Reactors”, Wiley Hill,
1981.
4. S. E. Liverhandt,
“Introduction to Nuclear Reactor Physics”
4.
Elective – III
1. ENERGY
CONSERVATION AND RECOVERY
Examination
Lectures
: - 4 hrs per week Theory : 100
Practical
/Oral Practical : -
Internal
: -
External
: -
1.
Energy conservation: An Introduction: Industrial energy use and economy,
Need for planning
energy, importance of energy in production and employment,
Importance of energy
cost in production, Energy and employment, The mystery
of conservation, (3
L)
2.
Indian energy scenario: Growth and demand of energy, Energy
availability,
Comparison of
specific energy use in select industry, Potential and status of
energy in India,
Energy saving potential in industries, Potential of energy
efficiency in India,
Barriers.(3 L)
3.
Energy available for industrial use and the role of conservation: Methodology
for
forecasting,
Industrial energy supply and demand, Review of alternative approaches and
major models and
studies, Method for forecasting industrial energy price and availability,
New energy
technologies and conservations.(3 L)
4.
Energy management and policy: Comprehensive energy
conservation planning
(CECP), Motivation
for Comprehensive energy planning, Principles of energy
conservations,
Procedure for Comprehensive energy conservation planning, Significance
of CECP, Tasks
required for CECP and application of CECP.(4L)
5.
Principles of energy conservation: Definition of energy
conservation, Principles of
energy conservations,
Economics of energy conservation policy, Optimum energy
conservation,
Observation on energy conservation by industry.(4L)
Section
ii
6.
Energy conservation technologies: Waste heat recovery and
utilization,
Technologies, Cost
and energy saving of waste heat recovery and utilization.(4L)
7.
Cogeneration concept and scope: Introduction, Advantages,
Constraints,
Feasibility, Scope,
Benefits and constraints.(3L)
8.
Energy audit and management: Types of audit,
Responsibility of energy
management, Targeting
and monitoring energy consumption, Scope of energy
audit, General
questionnaire, Case study of energy audit.(3L)
9
Energy conservation in utilities: Thermal and electrical
utilities and case studies of
stoichiometric amount
of air required for the burning of fuel. Theoretical air required for
Propane, equivalent
evaporation evaluation, Boiler efficiency evaluation by direct and
indirect method.
Theoretical air requirement evaluation on CO2 basis, Calculation of
blow down percentage,
Installation of economizer for boiler, Steam Balancing,
Optimization of steam
piping size to reduce pressure drop, Utilization of blow down
water to generate
flash steam, Steam use for power generation in an extraction cum
condensing turbine,
Excess air optimization, Waste heat recovery, Conversion of
electrical furnace in
to oil fired furnace, Insulation upgrade project, Annual fuel saving
by proper insulation,
Cost saving achieved by insulating uninsulated steam line,
Calculation
illustrating the most suitable insulation thickness, Improvement in specific
energy generation,(6L)
10.
Impact of climate change in India(3L)
11.
Energy conservation in Sugar Industry(3L)
12.
Energy conservation act 2001.(3L)
Reference
books:
1. A. D. Mohan Singh,
Col. S. K. Murthy (Retd.) and etc., “Energy Conservation in
Industries”, Module I
and II, AICTE, CEP, Code 358.
2. Devid Hu. S,
“Handbook of Energy Conservation”, McGraw Hill Publication.
3. Rao, Diwalkar
P.L., “Energy Conservation Handbook”, Utility Publication,
Hydrabad.
4. The Bulletion on
Energy Efficiency and Management by IRADA, MITCON,
MEDHA etc.
5. Amit Tagi, “A
Handbook Energy Audit”, Tata McGraw Hill publication, 2000
6. D. A. Reay, “Heat
Recovery Systems”, E and F. N. Spon ltd., 11, New Fetter
Lane, London, 1979.
7. A Practical Guide
to Energy Conservation, PCRA Publication, 2010.
L-INDICATES
LECTURE
5.
ELECTIVE – III
2.
POLYMER REACTION ENGINEERING.
Lectures
: - 4 hrs per week Examination
Practical
/Oral Theory : 100
Practical
: -
Internal
: -
External
: -
1. Introduction -
Conventional and Commercial approaches, Addition
polymerization
Kinetics, Condensation polymer kinetics, Ionic polymerization
kinetics,
Relationship between kinetic chain length and average degree of
polymerization.
2. Polyaddition
reactions - Kinetics and rates of polymerization of styrene,
Methyl methacrylate,
Ethylene, Polycondensation reactions –
Characteristics,
Homogeneous and heterogeneous polycondensation reaction
kinetics, Maximum
degree of polycondensation, Industrial polycondensation
3. Kinetics of chain
chemical reactions: Characteristics of chain reactions,
Stationary and non
stationary chain reactions, Kinetics of branched chain
reactions, Auto
acceleration and inhibition of chain kinetics, Kinetics of
inhibition
4. Copolymerization:
Introduction, Classification of copolymers, Basic
principles of
copolymers, Kinetics of copolymerization, Mayo's copolymer
equation,
Determination of feed and polymer, Determination of monomer
Reactivity ratios,
Copolymerization for limiting cases, Types of copolymesr
behavior, Overall
rate of copolymerization, Alfrey Price Q–e scheme,
Statistical
derivation of copolymerization equation, Range and applicability, of
copolymerization,
variation of copolymer composition with conversion and
applications of
copolymerization, Rates of copolymerization for chemical and
diffusion controlled
termination, Examples.
5. Introduction to
Smith- Ewart's emulsion polymerization kinetics, Experimental
techniques in
emulsion polymerization, Rates of polymerization for case I and
case II, Estimation
of total number of particles, Empirical correlations for
emulsion
polymerization, Vinyl Chloride suspension polymerization.
6. Reactors for
polymerization: Batch, PFR, CSTR with residence time,
average molecular
weight and control strategies, Programmed operation of
polyaddition
reactors, Low and high conversion reactors, Industrial
polymerization
reactors.
Text
Books:
1. G.N. Burnett,
“Mechanism of polymerisation reaction”, Interscience, 1954.
2. Anil Kumar, S.K.
Gupta, “Fundamentals of Polymer Science and Engineering”,
Wiley, 1978.
3. G.S. Misra,
“Introductory Polymer Chemistry”, Wiley Eastern Ltd.,New
Delhi,1993.
4. F. Wilkinson,
“Chemical Kinetics and Reaction Mechanism”, Van Norstrand
Reinhold Company Ltd,
England, 1980.
5. D.J. Williams,
“Polymer Science and Engg”. Prentice Hall, New York 1971.
6. F. Rodrigues,
“Principles of Polymers systems”, McGraw Hill, New York 1970
7. D.C. Miles,
“Polymer Technology”, Chemical Publishing New York, 1979.
8. George Odian,
“Principles of Polymerization”, 2nd Edition John Wiley and Sons,
New York 1981.
9. Fred Billmeyer, “A
Text Book of Polymer Science”, 3rd Edition, John Wiley and
Sons, New York, 1984.
5.
ELECTIVE – III
3.
PHARMACEUTICAL TECHNOLOGY-II
Examination
Lectures
: - 4 hrs per week Theory : 100
Practical
/Oral Practical : -
Internal
: -
External
: -
Medicinal chemistry,
Pattern of disease and drug action, Mode of action Clinical
application Chemistry
of hormones, Analgesics, and antipyretics
Synthesis of drug
molecules with selected types of reaction and writing the
synthetics giving
approximate condition and emphasis on Techno- commercially
potential routes.
Synthesis of some complex drug molecules (selected from vitamins and
alkaloids), Synthesis
of peptide drugs, Bio-organic chemistry of vitamins.
Raw materials and
Manufacturing processes for steroid drugs, Manufacturing
processes for some
excepients, eg. cellulose, and its derivatives, Lactose, Chirality and
chiral technology.
One topic of current interest, Effluent treatment
Raw materials for
Pharmaceutical Industry,.
Enzymes as catalyst
(a) in Synthesis for Pharmaceuticals (b) Introduction to
Principle of enzymes
catalyst, Lipases and esterase’s for hydrolytic conversion. Lipases
and esterase’s in
organic solvents, other hydrolytic reactions, Enzyme-catalyzed
oxidation reactions,
Enzyme-catalyzed C-X bond synthesis, Enzyme-catalyzed reduction,
Chiral Technology
Preformulation, Formulation, Evolution, Large scale manufacture and
packingwith focus on
equipment with reference to Oral sustained and controlled release
dosageforms and
Aerosols.
Introduction to Novel
drug Delivery Systems: Transdermal, Transmucosal,
Ophthalmic,
Colloidal: Liposome’s, nanoparticles, emulsion systems etc
Introduction to Radio
pharmaceuticals, Overview of cosmetic products
Novel Drug Delivery
Systems, Oral sustained and controlled release dosage
forms, Aerosols, Blood
products, Glandular products, Radiopharmaceuticals, Surgical
sutures, ligatures,
dressings. Physiology of Central Nervous System and Drugs acting on
Central Nervous
System.
Books:
1. Pharmaceutical
Dosage Forms And Drug Delivery Systems, Ansel, Philadelphia,
Fea and Febiger, 1985
2. Introduction to
Pharmaceutical Dosage Forms Ansel, Henry Kimpton Publishers,
London.
3. Pharmaceutics: The
Science of Dosage Form Design Aulton, New Delhi, B.I.
Naverly Pvt. Ltd.,
1995
4. Modern
Pharmaceutics G.S. Banker New York, Marcel Dekker1990
5. Bentely’s Textbook
of Pharmaceutics Rawlins Cassell Ltd, London
6. Fundamentals of
Pharmacy Blome H.E. Philadelphia, Fea and Febiger, 1985
7. Fundamentals of
Pharmacy Blome H.E. Philadelphia, Fea and Febiger, 1985
8. Pharmaceutial
Production Facilities: Design and Applications G.C.Cole
9. New York Ellis
Horwood 1990
10. Husa’s
Pharmaceutical Dispensing Martin E.W. Easton Mack Pub. Co. 1971
11. Transdermal
Delivery of Drugs A.Kydonieus Florida, CRC Press, 1987
12. Transdermal Controlled
System Medications Y.W.Chien, New York, Marcel
Dekker 1987
13. Quantitative
Pharmaceutical Chemistry, Glann L. Jenkins, Adelbert M. (VI
Edition) McGraw-Hill
Books Company
14. Text Book of
Pharmaceutical Analysis, Kenneth A., Connors, A Willey
Interscience
Publication, USA
15. Wolfgang Aehle, “
Enzymes in Industry Production and Applications” Wiley
VCH Publication, 2003
16. Heinrich Klefenz,
”Industrial Pharmaceutical Biotechnology” Wiley-VCH
Publication, 2002.
17. T. Scheper,
“Process Integration in Biochemical Engineering” Springer
Publication, 2003.
18. Oligan Repic,
“Principles of Research and Chemical Development in the
Pharmaceutical
Industry Wiley Interscience 1998
19. Romano Di Fabio,
“From Bench to Market the Evolution Chemical Synthesis”
Oxford University
Press, 2000
5.
ELECTIVE – III
4.
MULTIPHASE REACTOR DESIGN
Examination
Lectures
: - 4 hrs per week Theory : 100
Practical
/Oral Practical : -
Internal
: -
External
: -
1. Introduction:
Reaction kinetics for multiphase reactions, Brief idea about
multiphase reactors
and design considerations, Catalyst deactivation and
regeneration.
2. Review of reaction
kinetics and reactor design
3. Industrial
reactors: Trickle bed, Bubble column, segmented bed, Agitated
slurry, Fluidized bed
and slurry reactors, Constructional features and
operation (Batch and
continuous)
4. Models for
analysis gas – liquid and gas – liquid – solid reactions, Film and
penetration theories,
Transport resistances and heat effects.
5. Residence time
distributions (RTD) and macro mixing models, Review of
methods obtaining
RTD, Problems in scale-up.
6. Models for gas –
liquid – solid reactors (Only model formulations with
assumption and final
design equations wherever available. Numerical
solutions of model
equation excluded).
7. Brief description
of laboratory reactors and significance of laboratory data for
reactor design and
scale-up.
8. Intrinsic
kinetics: Catalysis, Langmuir – Hinshelwood models, Catalyst
pellets, Effective
diffusivity, Tortuosity, Effectiveness factors, Mass transfer
and reaction in
packed beds, Determination of limiting step from reaction
data, Introduction to
chemical vapor deposition reactors.
Books:
1. Y.T. Shaha, “Gas
Liquid Reactor Design”, McGraw Hill, 1979
2. Foggler, “Elements
of Chemical Reaction Engineering”, Prentice Hall of India.
References:
1. Westerterp K.R.,
Van Swaaij and Beevackers, “Chemical Reactor Design and
Operation”, John
Wiley and Sons, 1978
2. Carberry, Verma,
“Chemical Reactions and Reaction Engineering”, Marcell
Decker, 1987
3. Gianetta and
Silverton, “Multiphase Chemical Reactor – Theory, Design,
Scale-up”, Hemisphere
Publishing Corporation, 1986
4. Sharma and
Doraiswamy, “Heterogeneous Reactions”, Vol. I and II, John
Wiley, 1984
5.
ELECTIVE – III
5.
MASS TRANSFER WITH CHEMICAL REACTON
Examination
Lectures
: - 4 hrs per week Theory : 100
Practical
/Oral Practical : -
Internal
: -
External
: -
Section
– I
Theory of
simultaneous mass transfer and chemical reaction, Film theory,
Penetration and
surface renewal theory, Higbe’s model and Danckwaert’s model,
Absorption with
chemical reaction (gas-liquid systems) and extraction with chemical
reaction
(liquid-liquid systems), Very slow reaction regime (Kinetic regime), Slow
reaction regime, Fast
reaction regime, Instantaneous reaction regime, Physico -
chemical data,
Prediction and estimation of diffusivity and solubility of gases in pure
liquids and
solutions.
Section
– II
Model experiments on
absorption and extraction with chemical reaction, Use
of wetted wall
column, Laminar jet, Disc column multiple sphere absorber, Stirred
cell, Application of
theory for studying the kinetics of heterogeneous reaction and
determination of mass
transfer coefficient and interfacial areas by chemical method,
Characteristic and
design criteria for industrial equipment used for absorption and
extraction
accompanied by chemical reaction, Typical examples and case liquid –
liquid systems.
References:
1. G. Astrita, “Mass
Transfer with Chemical Reaction Engineering”, Elasevier
Amsterdam, 1966
2. P. V. Danckwarts,
“Gas Liquid Reactions”, McGraw Hill, 1970.
3. Dr. Sharma, M. M.,
“Advances in Mass Transfer”
6.
ADVANCED SEPARATION PROCESSES
Examination
Lectures
: - 1 hrs per week Theory : --
Practical
/Oral : 2 hrs. Practical :
Internal
: 25
External
: 25
Introduction
to advanced separation techniques such as :
1) Reverse Osmosis
2) Ultra filtration
3) Micro filtration
4) Pressure swing
Adsorption
5) Electrostatic
Precipitator
6) Supported Liquid
Membranes
7) Supercritical
Fluid Extraction etc.
Study of basic principles
& different working modules used in above
separation
techniques.
List
of practicals:
1. Ultrafiltration of
some dilute solutions.
2. Reverse osmosis of
saline solution.
3. Microfiltration of
raw material.
4. Electrodialysis.
5. Pressure swing
Adsorption.
6. Electrostatic
precipitator.
7. Gas
Chromatography.
8. Supported liquid
membranes.
9. Ion Exchange.
Books:
1. C.J.King
"Separation Processes" 2nd Ed., Tata McGraw Hill Publishing Co. Ltd.,
New Delhi, 1986.
2. Sirkar K. &
Winston H.O. "Membrane Hand Book" Van Nostrand Reinhold,
New York, 1992.
3. McCabe & Smith
"Unit Operations of Chemical Engineering" 5th
Ed.,McGraw Hill
International .
4. Richardson and
Coulson,“Chemical Engineering Volume –II”,Pergamon
Press,1970.
5. Schweitzer P.A ,
“Handbook of Separation Techniques for Chemical
Engineering” 2nd
edn.,McGraw Hill Book Co.,1986.
6. Souri Rajan S.
"Reverse Osmosis" Logos Press Ltd.
7.
PROJECT WORK
Examination:
Lectures:
-- Theory: --
Practical
/Oral
Practical: 6
hrs/week Internal : 50
External:
100
The project work is
to be completed under the guidance of a staff
member and /or staff
members and submit a typed report in duplicate.
The Project Report
consists of
1) Certificate
2) Acknowledgement
3) Statement of
Problem
4) Synopsis /
Abstract.
5) Index.
6) Introduction.
Importance of
Project.
Market Situation.
Consumption Data.
Need of such Plant.
7) Literature survey
– Process Selection.
8) Theoretical
conditions – Process Parameters, Composition.
9) Process
Description – Process Floe-sheet ( Block Diagram)
10) Basic Engg. Data.
Physical.
Chemical.
Thermodynamic.
Analytical Methods.
11) Details of
Experimental Set up & Experimental Work.- Purpose method,
Chemicals,
Calculations, Analysis of Data, Results, Discussion.
12) Material Balance
& Energy Balance.
13) Selection of
Equipments & Specifications.
14) Design of
Specific Equipment.
Process design.
Mechanical Design.
15) Control &
Safety of Process.
16) Plant layout
& Location.
17) Cost Estimation
& Economic Analysis
18) Pollution
Control, Safety, Marketing
19) Conclusion &
Remarks.
20) References.
Books.
Journals.
21) Appendix.
List of Tables.
Sample Calculation.
Data Tables, etc.
The object of the
project is to make use of the knowledge gained by the
student at various
stages of the degree course. This helps to judge the level
of proficiency,
originality and capacity for application of the knowledge
attained by the
student at the end of the course.
Each group should
consist of maximum 3 students.
For term-work (Internal)
75 marks, the
assessment should be by conducting frequent written tests,
seminars during the
year & an oral exam. at the end of the year conducted
by all the staff
members of the dept. The Head of the Dept. should see that
the assessment
procedure should be the same for all the students of the class.
For external 75
marks, the project work shall be assessed by an oral exam.
to be held by at last
two examiners, one internal and one external preferably from
industry at the end
of the year.
The object of the
VIVA VOCE examination (Internal and External Orals) is to
determine whether the
objectives of the project work have been met by the
student as well as to
assess the originality and initiative of the student as
demonstrated in the
project work.
