304 EMERGING TRENDS IN BIOTECHNOLOGY
Unit I
1. Genome & Genomics: Concept and methods of genome analysis, genome projects.
2. Transcriptome & Transcriptomics: Concept and methods
3. Proteome & Proteomics: Concept and methods of Proteome analysis
4. Metabolome & Metabolomics
Unit II
1. Stem Cell technology: Types of stem cells
2. Manipulations of stem cells and applications in medicine
3. In vitro fertilization: Principle, methods, applications and ethics.
4. Cloning of animals: Methods and applications.
Unit III
1. Nano biotechnology: Introduction, Biomaterials and biological materials-examples and
uses
2. DNA nanotechnology-structural DNA assembly-Nanopore and
3. Nanoparticles-biological arrays- nanoprobes for analytical applications
4. Nano biosensors-nanoscale organization-characterization-quantum size effects- sensors
of the future.
5. Tools for measuring nanostructures. Microscopies-SEM-TEM-AFM modern advancesmicroanalysis-
optical detection of single molecules
Unit IV
1. Microarray chips: Concept, design of biochip, types of DNA chips
2. Gene Therapy for Human Diseases.
3. Protein Crystallization; Theory and methods: API Electro spray and MALDI-TOF.
4. SNP’s and GMS (Genome mismatch Signals)
Unit V
1. Biosensors: Concept, principle, Organization of biosensors
& types
2. Biosensors: Health & Medicine
3. Biosensors: Food technology, Environment monitoring
4. Bacterial biosensors; Array Biosensors
Practical Exercises: Appropriate exercises based on theory
Reference Books
1. DNA Microarrays and gene expression by P. Baldi & GW Hatfield
2. Protein – Protein Interactions by Erica Golemis
3. A passion for DNA (Genesm genomes and Society) By JD Watson
4. Modern Genetic analysis by Anthony JF Griffiths et al.
5. Nan biotechnology- next big idea by Mark, Ratner Daniel Ratner
6. Gene cloning by TA Brown
7. Latest information on academic Web sites.
Note: All books are of latest editions
305. Lab Course V
Consists of practical exercises listed out under 301 & 302
306. Lab Course VI
Consists of practical exercises listed out under 303 & 304
