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Paper I : Research Methodology IFor Life Sciencesl
Total Credits : 4
1, lntroduction to Research Design
Nature and objectives of research, Methods of research: Historical, descriptive and
experimental, research process, research approaches, criteria for good research, meaning of
resaerch design, features of good design, differentresearch designs and basic principles of
experimental designs, design of experiments.
2. Data Collection and Analysis
Types of data, methods and techniques of data collection, primary and secondary data, meta
analysis, historical methods, content analysis, devices usedin data collection, pilot study and
pretests of tools, choice of data collection methods.
Data Processing and Analysis
Measures of Central Tendency, Measures of Dispersion, Measures of Variation, Measures of
Central Tendency vs Meaures of Dispersion, Normal Distribution, Measures of Skewness and
lnterpretation, Correlation and Regression: Types and Applications.
Test of Signification
Significance of difference in means, Standard Deviation and Standard Error; Z-test, 't' test, and
chi square test: Purpose and use, Analysis ofVariance.
Paper writing and report generation
Basic concept of paper/ thesis writing and report generation, writing Research Abstract,
lntroduction, Review of Literature, Results, Conclusion, Concepts of Bibliography and
References, Significance of Report writing, Types of Research Reports, Methods of presentation
of Reports, Formats for Publication in Research Journals.
Reference Books*
1. Research Methodology: Methods and Techniques- C.R.Kothari, Nre Age publishers.
2. Research Methodology- R.N.Trivediand D.P.5hukla, College Book Depot, jaipur
3. Research Methodology- D. Chakraborty, Lotus Press
4. Research Methodology for Life Sciences- N.Arumugam, Saras publications
5. Random Data Analysis and Measurement ProceduresBendat and Pcrsol, Wiley lnterscience
Methods in Biostatistics- B.K.Mahajan, J.p. Brothers Medicar publishers' N Delhi' lndia
-J W'Creswell' SAGE Publications' INC'
Principles of Biostatistics-*Latest Edition of the Books
Ph.D. Course Work
Paper ll : Computer Applications and Bioinformatics IFor life Sciences]
Ph.D, Course Work-Biochemistry-: Session 2020"21-page No. 4
3. Computer Fundamentals
Computer Basics and Terminology, lnput and Output Devices, Computer memory, Computer
generatioon and crassification, Types of software, operating System, Their Types, Basic Terms related to Windows OS, Computer Netwroks, LAN, l\lAN. WAN
Reserach Porishing Toors: MS word, creatin,, editinS and saving a word document, use of
Autotext, Tables related Operations, Graphics.
lntroduction to Spreadsheet and presentation
lntroduction to Excel, Use of Spreadsheet in Research, Dta Storing, Various Data Types, Use of
Formula and Functions, Calculation, Manipulation and Analysis of Data, preparing Cha,.s, MS Power Point, Features and Functions, Creating presentations, Animation, Customizing
Presentation.
lntroduction to lnternet and presentation
lntroduction to lnternet, WWW, Searching on lnternet, Literature survey, Websites, Search
Engines, Anti-Plagarism Software, Viruses and its Types, protection from Viruses
lntroduction of computers in Research: Literature search using various search Engines, writing
References, Software for Reference Arrangement, Statistical packaBes: Sigma plot etc.
Bioinformatics
Applications of Bioinformatics in Life sciences, Biorogicar Database: primary, secondary and
composite Database, sequence Database: Nucreic acid (EMBL and GenBank), protein Database
(PlR and SWISS-pORT), Structure Database: protein Data Bank.
sequence Analysis: Biorogicar Motivation of sequence Anarysis, omorogy, Base pair Arignment:
Local, Global and Toors for Base pair Alignment: BLAST and FASTA, Murtipre sequence Arignment
Methods.
Phylogenetic Analysis, protein Structure prediction, Drug Designing
Phylogenetic Analysis: Methods, character based and distance based methodsTree evaruation,
Protein Structure predictions: homology modeling, treading, ab_initio methods,
Expression sequence Tags (EST) and its Applications, Microarray Database and its Applications
Reference Books+
L. An lntroduction to Computational Biochemistry- C. Stan and T.Sal
2. lntroduction to Bioinormatics: A Theoretical and practical Approach- s.A.Krawetz
D. D.Womble
3. Bioinformatics: Genes, Proteins and Computer- C.A.Orengo, D.T. Jopnes, J.M. Thornton 4. lnstant Notes on Bioinformatics- D.R.Westhead, J.M.perish, R.M.Toyman
5. Essential Bioinformatics- Jin Xiong
6. An lntroduction to Bioinformatics Algorithms- N.C. Jones, p. pevzner
7. Bioinformatics: Sequence and Genome Analysis- D.W.Mount
8. Statistical Metods in Bioinformatics: An lntroduction- S.Misener, S.A.Krawetz
9. Bioinformatics: Database and Algorithms- N.Gautham
10. Bioinformatics Technology: yi-ping phoebeChen
11. Data Mining: Multimedia, Softcomputing and Bioinformatics: S.Mitra, T. Acharya
xLatest Edition of the Books
Ph.D. Course Work
Paper lll : Advances in Biochemistry
Total: 3 Credits
1. Advance Chromatography Techniques: Principle and Applications of LCMs, HPTLC, FpLC
2. Advance Microscopy Techniques: Electron Microscopy, Confocal Microscopy
3. Flow Cytometry: Basic Principle and Applications
4. Quantitative DNA Amplification: Basic Principle and Applications of RealTime PCR
5. Na nobiotechnoloy: Nanomaterials, types, methods of synthesis and cha ra cte rizatio n of
nanoparticles, applications in diagnostics, therapy, agriculture etc.
6. Biosensors: Principle, types and applications
7. Probiotics: Probiotics in healthy food, functionalfood
8. Latest Techniques in Molecular Biology: Next generation DNA sequencing, CRySpR
9. Bioethics: Ethical, legaland social issues related to biological research
10. Drug Discovery: Overview of Drug Discovery from natural products, drug development and
pharmacokiteics, preclinical and clinical trials.
11. System Toxicology: Realworls applications and opportunities
12. Toxicogenomics: lntroduction, scope, applications and limitations
13. Toxicokinetics/ Pharmacokinetics of drugs, toxins. Toxicants etc; Hazard evation and risk
assessment, safety measures
14. Bioreactors: Principle of bioprocesses, design and types of fermenters, Nutrient media and ' growth optimization, downstream processes, analysis of different types of fermented products
15. Phytoactive compounds from plants: tupes and classification, their therapeutic signiflcance
16. Animal models for life style disorders like diabetes melllitus, hepatic disorders rheumatoid
arthritis etc. Role of toxicology, pha rmacokinetics and preclinical studies in reference to these
disorders.
17. Reproductive system: Basics, immunology of male and female reproductive systems
18. Fetus as alloBraft: Paradox of pregnancy, im m unod iagnotics, immunology of reproduction
19. lnfertility and foetal wastage, lntifertility vaccines
Note: The course will include lectures, discussions and seminars, There is no assigned text for the
course. The information will be taught from examples of recent advancesreported in the current
scientific letrature and/ or drawn frm various textbook/ internet sources.
